DEPOT MEDROXYPROGESTERONE ACETATE (DMPA) ENHANCES SUSCEPTIBILITY AND INCREASES THE WINDOW OF VULNERABILITY TO HIV-1 IN HUMANIZED MICE

Depot medroxyprogesterone acetate (DMPA) enhances susceptibility and increases the window of vulnerability to HIV-1 in humanized mice

Abstract The progestin-based hormonal contraceptive Depot Medroxyprogesterone Acetate (DMPA) is widely used in sub-Saharan Africa, where HIV-1 is endemic.Meta-analyses have shown that women using DMPA are 40% more likely than women not using hormonal contraceptives to acquire Human Immunodeficiency Virus (HIV-1).Therefore understanding how DMPA inc

read more



Strengthening individual and family resilience against leprosy-related discrimination: A pilot intervention study.

BackgroundLeprosy and leprosy-related stigma can have a major impact on psychosocial wellbeing of persons affected and their family members.Resilience is a process that incorporates many of the core skills and abilities which may enable people to address stigma and discrimination.The current study aimed to develop and pilot an intervention to stren

read more

Smart Optical Catheters for Epidurals

Placing the needle inside the epidural space for locoregional anesthesia is a challenging procedure, which even today is left to the expertise of the operator.Recently, we have Ice Chute Delay Mechanism demonstrated that the use of optically sensorized needles significantly improves the effectiveness of this procedure.Here, we propose an optimized

read more